Association of Angiotensinogen M235T Gene variants, and Plasma Renin Activity with Preeclampsia
نویسندگان
چکیده
منابع مشابه
Angiotensinogen M235T gene variants and its association with essential hypertension and plasma renin activity in Malaysian subjects: A case control study
BACKGROUND Essential hypertension is a major public health concern worldwide where its prevalence accounts for various cerebrovascular diseases. A common molecular variant of angiotensinogen (AGT), the precursor of potent vasoactive hormone angiotensin II, has been incriminated as a marker for genetic predisposition to essential hypertension in some ethnics. This case-control study was designed...
متن کاملContribution of angiotensinogen M235T and T174M gene variants and haplotypes to preeclampsia and its severity in (North African) Tunisians
BACKGROUND Preeclampsia (PE) is a pregnancy-associated hypertensive disorder and a leading cause of maternal and neonatal morbidity and mortality. While its pathogenesis remains ill defined, several candidate genes for PE have been identified, but results remain inconclusive. We investigated the association of the angiotensinogen ( AGT) gene variants M235T and T174M with PE, and we analyzed the...
متن کاملAssociation between Angiotensinogen M235T Polymorphism and Preeclampsia in Iranian Pregnant Women
OBJECTIVE To determine the possible association between the M235T variant of angiotensinogen gene and preeclampsia in Iranian preeclamtic women with hypertension during pregnancy. MATERIALS AND METHODS During a case control study, we used polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) analysis to investigate the association between M235T polymorphism in pr...
متن کاملassociation between angiotensinogen m235t polymorphism and preeclampsia in iranian pregnant women.
objective: to determine the possible association between the m235t variant of angiotensinogen gene and preeclampsia in iranian preeclamtic women with hypertension during pregnancy. mand methods: during a case control study, we used polymerase chain reaction-based restriction fragment length polymorphism (pcr-rflp) analysis to investigate the association between m235t polymorphism in preeclamtic...
متن کاملGender-specific association of M235T polymorphism in angiotensinogen gene and diabetic nephropathy in NIDDM.
This study examined the association between the development of nephropathy in non-insulin-dependent diabetes mellitus (NIDDM) patients and M235T polymorphism in the angiotensinogen gene. White NIDDM patients with diabetic nephropathy (case subjects, n = 117) and patients without any evidence of nephropathy and > or = 10 years of NIDDM (control subjects, n = 125) were selected from among patient...
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ژورنال
عنوان ژورنال: Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
سال: 2014
ISSN: 2090-083X
DOI: 10.21608/eajbsc.2014.16055